Natural Alternatives to Benadryl for Dog Allergies: A Dog Parent Guide

Dog allergies are super common, and they show up as anything from runny noses and irritated skin to persistent scratching and even an upset stomach. And while many pet owners reach for a quick dose of Benadryl, there are natural remedies available that offer lasting relief without relying on pharmaceutical antihistamines.

This article discusses the factors that lead to dog allergies, the reasons why one thinks about taking a natural approach, and the steps to take to find the most effective and natural way to alleviate the dog’s symptoms.

Understanding Dog Allergies

Dogs have allergies when their immune system overreacts to chemicals it believes to be dangerous even if they are benign. From pollen to dust mites, these environmental allergens lead to what’s called an “immune response”, and that’s what brings on all the uncomfortable symptoms. A retrospective study from the journal of Veterinary Dermitology showed that “Positive reactions to house dust mites and moulds are the most common types of dog allergies,” (Zur, G., et al., 2002). 

Listed below are some typical offenders behind dog allergies.

Environmental Allergens: Think pollen, dust mites, mold, and even certain grasses. These trigger respiratory allergies or skin reactions, especially if a pup spends a lot of time outdoors.

Food Allergies: Just like in humans, some dogs have food allergies or sensitivities to food ingredients. A literature review concluded that “The most common food allergens contributing to canine CAFRs are beef, dairy products, chicken, and wheat,” (Mueller, R., Olivry, T., & Prélaud, P., 2016). These often show up as itchy skin, gastrointestinal issues, or even chronic inflammation. 

Flea Allergy Dermatitis: Some dogs are highly sensitive to flea bites, and a single bite triggers intense itching and skin irritation, leading to sores or even hair loss. 

Acute Allergies: Serious symptoms that occasionally call for emergency care are brought on by allergic responses to certain immunizations, drugs, or bug stings. 

Identifying the type of allergy is half the battle—then comes managing it effectively, which brings natural alternatives!

Why Consider a Natural Alternative to Benadryl?

Pharmaceutical antihistamines like Benadryl temporarily relieve symptoms, but they often come with side effects. “Common side effects of diphenhydramine hydrochloride in dogs include lethargy, hyperactivity, agitation, hyperthermia, ataxia, tremors, and fasciculations, and tachycardia,” (Worth, A., Wismer, T., & Dorman, D., 2016). Furthermore, although Benadryl seems like a quick treatment, it doesn’t address the immunological reactions that underlie the symptoms. In order to treat allergies in a sustainable manner, more pet owners are looking at natural options.

Top Natural Remedies for Dog Allergies

Some of the best natural options are presented below. Thay are packed with anti-inflammatory properties, immune-boosting effects, and histamine-regulating power to help relieve a dog’s discomfort.

Quercetin: Nature’s Benadryl

Known as one of the most powerful natural antihistamines, quercetin is a flavonoid that has “anti-allergic functions by inhibiting histamine production, pro-inflammatory mediators, and regulating Th1/Th2 stability,” effectively blocking the allergic response that makes a dog itchy (Jafarinia, M., et al., 2020). 

It’s found in foods like apples, berries, and parsley, and it’s available in supplement form (usually with bromelain for better absorption). Quercetin helps the immune system function in addition to easing allergy symptoms.

Nettle: Anti-Allergy Herb

Nettle is packed with histamine and anti-inflammatory compounds that reduce sensitivity to allergens over time. (Roschek, B., et al., 2009).

This herb also has loads of vitamins, like A, C, and D, and it supports overall immune health. It is prepared as tea, dry herb, or sautéed nettle.

Best for: Dogs with seasonal allergies or sensitivities to environmental allergens.

Omega-3 Fatty Acids: Essential Oils for Allergy Relief

Found in fish oil, krill oil, and flaxseed oil, omega-3s are essential for reducing inflammation, which calms down the itchy-scratchy cycle common in dogs with allergies.

These fatty acids are great for managing allergies and support joint health, heart health, and even brain function (Bauer, J., 2007).

How to Use: Add a few drops of omega-3 oil to the dog’s food. It’s ideal to start slow and monitor for any stomach upset.

CBD Oil: Calming and Healing in One

CBD interacts with the dog’s endocannabinoid system, helping to regulate immune responses and reduce inflammation. Studies suggest that CBD oil reduce pruritus in dogs with atopic dermatitis but does not significantly affect skin lesions (Loewinger, M., et al., 2022).

CBD oil is potentially beneficial for dogs with chronic allergies and related stress, as it helps soothe both physical and emotional symptoms.

L-Theanine: Relaxing Antihistamine Alternative

This amino acid found in green tea moderates the histamine response and helps calm dogs who feel anxious due to itching or discomfort. Studies suggest that L-theanine has anti-inflammatory, anti-stress, and immune-regulating properties that alleviate allergic responses and improve overall health (Hwang, Y., et al., 2017; Chen, S., et al., 2023).

 L-theanine is best given in tablet form, but make sure it’s dog-safe and free of xylitol, which is toxic to dogs.

Chinese Skullcap: Anti-Inflammatory Powerhouse

This herb isn’t just for humans! Chinese skullcap has potent antihistamine properties that help reduce histamine levels and control inflammation in a dog’s body. An in vitro trial showed that “The hexane fraction of skullcap inhibits allergen permeation and regulates immune responses, with linoleic acid being the most important fatty acid responsible for these effects,” (Jung, S., et al., 2017).  

Typically available in tincture form, it is an effective addition to an allergy-fighting toolkit.

Additional Natural Remedies Worth Considering

When it comes to allergies, sometimes a one-size-fits-all approach just doesn’t cut it. A multi-pronged strategy, combining several natural remedies, give a dog’s health a real boost. A few more options in managing a dog’s allergies effectively and naturally are listed below.

Irish Moss – Nature’s Skin Soother

Irish moss, a seaweed packed with vitamins, minerals, and antioxidants, is excellent for supporting skin health, especially if a dog suffers from chronic itchy, irritated skin.

Irish moss contains essential nutrients like iodine, magnesium, and vitamins A and E, all of which play a role in reducing inflammation and supporting the immune system by inhibiting collagenase and tyrosinase activity, which are involved in skin aging and pigmentation (Marques, R., et al., 2021). Because it’s rich in antioxidants, Irish moss also help combat oxidative stress, which often exacerbates allergy symptoms.

How to Use: Irish moss is purchased in dried powder form. Add a small scoop to a dog’s food, adjusting the amount to a dog’s weight for optimal results. Be sure to monitor a dog for any adverse reactions when introducing this new supplement.

Benefits: Irish moss not only helps calm itchy skin but also supports thyroid function, which is crucial for regulating the immune system and preventing allergic responses. With consistent use, Irish moss  help manage a dog’s seasonal or environmental allergies and improve overall skin and coat health.

Apple Cider Vinegar – Topical & Internal Relief

Apple cider vinegar (ACV) is a versatile solution for dogs with allergy symptoms, both inside and out. ACV has natural antibacterial and antifungal properties that help improve the skin’s barrier against allergens, reducing itching and irritation. By lowering skin pH, ACV helps create an environment less hospitable to irritants, all while balancing gut health if added to a dog’s water. 

How to Use: For topical application, dilute ACV with water in a 50:50 ratio and spray or dab it onto irritated areas of a dog’s skin. For internal support, add a small amount to the dog’s water bowl. Always start with a small dose and monitor the pet’s response.

Benefits: Apple cider vinegar not only soothes itchy, irritated skin but also boost the dog’s immune health from the inside out. Regular use, both topically and internally, help improve gut health, which is directly linked to a stronger immune response against allergens.

Curcumin – Anti-Inflammatory Powerhouse

Curcumin, the active compound in turmeric, is one of nature’s most powerful anti-inflammatory agents, making it ideal for addressing allergy symptoms that stem from chronic inflammation. With its potent antioxidant properties, curcumin supports a dog’s immune system, making it less susceptible to allergic reactions. It also helps limit histamine release, reducing the likelihood of an allergic response in the first place (Kurup, V., & Barrios, C., 2008). 

How to Use: Add a dash of turmeric powder to a dog’s food, around 1/8 to 1/4 teaspoon per 10 pounds of body weight. Because curcumin is more bioavailable when combined with fat, consider adding a small amount of olive or coconut oil along with it.

Benefits: Curcumin helps reduce inflammation in the dog’s body, supporting immune health and preventing the chronic itching, redness, and irritation caused by allergies. Over time, it is a great addition to an allergy management regimen and even help with other inflammatory issues like arthritis.

Beta-Sitosterol – Immune-Modulating Magic

As a plant-based sterol with immune-modulating qualities, beta-sitosterol is very good at regulating allergic dogs’ immunological reactions. A study showed that “β -Sitosterol alleviates allergic symptoms and intestinal inflammation in mice by improving intestinal barrier function and reversing gut microbiota remodeling,” (Ma, L., Ma, Y., & Liu, Y., 2023). 

How to Use: Beta-sitosterol is available in supplement form and used according to the dog’s weight and the product instructions. As with all supplements, start with a low dose and consult the dog’s veterinarian to find the right balance for a dog.

Benefits: Beta-sitosterol is especially helpful for dogs with hypersensitive immune systems, as it promotes a balanced response, reducing the severity of allergic symptoms. Its immune-modulating properties also make it useful for long-term allergy management, helping to support a dog’s resilience to seasonal or environmental allergens.

Choosing the Right Remedy for A Dog’s Unique Needs

Every dog’s allergies are unique. What works wonders for one is not necessarily as effective for another, so it’s important to find the best natural alternative for a pup. Start with one or two remedies, monitor the dog’s response, and adjust as needed. When in doubt, consult the dog’s vet, especially if a dog is already on medications or has underlying conditions like kidney disease.

Factors to Consider

The severity of Symptoms: Some mild, occasional symptoms need seasonal solutions, whereas chronic allergies require a more consistent remedy.

Dog’s Weight: Dosages for many natural remedies are often based on the dog’s body weight, so be sure to calculate carefully.

Diet: The dog’s food either help or hinder their allergy symptoms. Consider avoiding common food allergens and focus on a wholesome diet rich in immune-supporting nutrients.

Tips for Managing Dog Allergies Day-to-Day

Clean Their Environment: Regular cleaning helps reduce environmental allergens like dust mites and pollen, especially during allergy season.

Stay on Top of Flea Prevention: Flea bites are a major source of allergic responses in dogs, so make sure to use safe flea prevention methods.

Support Gut Health: A healthy gut improves immune function, so consider adding probiotics to a dog’s diet. Probiotics are available in powdered form and is easily mixed into meals.

Be Patient: Natural remedies often take time to show their full effects. Stick with it, and give the dog’s body time to respond.

Final Thoughts: Go Natural, Go Proactive

Managing dog allergies takes a bit of patience and experimentation to find what truly benefits a furry friend. Each dog’s immune system responds differently, so it’s important to observe, adjust, and choose remedies that fit their unique needs. Natural remedies, while slower to show results than pharmaceuticals, support the immune system, reduce inflammation, and offer long-term health benefits.

Since natural solutions don’t provide instant relief, consistency and regularity are essential. By carefully introducing and monitoring these remedies, pet parents make a meaningful difference, helping a dog live a healthier, more comfortable life with reduced allergy-related issues. Natural solutions are a commitment but leads to a happier, itch-free pet.

References

• Bauer, J. (2007). Responses of dogs to dietary omega-3 fatty acids.. Journal of the American Veterinary Medical Association, 231 11, 1657-61 . https://doi.org/10.2460/JAVMA.231.11.1657.
• Jung, S., Lee, S., Choi, D., See, H., Kwon, D., Do, J., Shon, D., & Shin, H. (2017). Skullcap (Scutellaria baicalensis) Hexane Fraction Inhibits the Permeation of Ovalbumin and Regulates Th1/2 Immune Responses. Nutrients, 9. https://doi.org/10.3390/nu9111184.
• Kurup, V., & Barrios, C. (2008). Immunomodulatory effects of curcumin in allergy.. Molecular nutrition & food research, 52 9, 1031-9 . https://doi.org/10.1002/mnfr.200700293.
• Loewinger, M., Wakshlag, J., Bowden, D., Peters-Kennedy, J., & Rosenberg, A. (2022). The effect of a mixed cannabidiol and cannabidiolic acid based oil on client‐owned dogs with atopic dermatitis. Veterinary Dermatology, 33, 329 – e77. https://doi.org/10.1111/vde.13077.
• Ma, L., Ma, Y., & Liu, Y. (2023). β-Sitosterol protects against food allergic response in BALB/c mice by regulating the intestinal barrier function and reconstructing the gut microbiota structure.. Food & function. https://doi.org/10.1039/d3fo00772c.
• Marques, R., Guillaumin, A., Abdelwahab, A., Salwiński, A., Gotfredsen, C., Bourgaud, F., Enemark-Rasmussen, K., Miguel, S., & Simonsen, H. (2021). Collagenase and Tyrosinase Inhibitory Effect of Isolated Constituents from the Moss Polytrichum formosum. Plants, 10. https://doi.org/10.3390/plants10071271.
• Mueller, R., Olivry, T., & Prélaud, P. (2016). Critically appraised topic on adverse food reactions of companion animals (2): common food allergen sources in dogs and cats. BMC Veterinary Research, 12. https://doi.org/10.1186/s12917-016-0633-8.
• Roschek, B., Fink, R., McMichael, M., & Alberte, R. (2009). Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis. Phytotherapy Research, 23. https://doi.org/10.1002/ptr.2763.
• Worth, A., Wismer, T., & Dorman, D. (2016). Diphenhydramine exposure in dogs: 621 cases (2008-2013).. Journal of the American Veterinary Medical Association, 249 1, 77-82. https://doi.org/10.2460/javma.249.1.77.
• Zur, G., Ihrke, P., White, S., & Kass, P. (2002). Canine atopic dermatitis: a retrospective study of 266 cases examined at the University of California, Davis, 1992-1998. Part I. Clinical features and allergy testing results.. Veterinary dermatology, 13 2, 89-102. https://doi.org/10.1046/J.1365-3164.2002.00285.X.